Tuesday, 19 April 2011

Report: Complaint to the relevant executive editor of the Lancet about the PACE Trial articles published by the Lancet

Submitted by Malcolm Hooper, Emeritus Professor of Medicinal Chemistry (March 2011; made public April 2011)

(With grateful acknowledgment to members of the ME/CFS community)


"In 1996 when psychiatrists Drs. Peter White and Simon Wessely co-authored a review of “Chronic Fatigue Syndrome” (Joint Royal Colleges Report, CR54, October 1996), a Lancet editorial roundly condemned the publication (“Frustrating survey of chronic fatigue”, Volume 348, Issue 9033, Page 971, 12 October 1996): “Psychiatry has won the day for now …. The sixteen-strong committee was top-heavy with psychiatric experts, so the emphasis on psychological causes and management is no surprise …. We believe that the report was haphazardly set-up, biased, and inconclusive, and is of little help to patients or their physicians”.

"In 2011, when Professors White and Wessely collaborated in a multi-centre trial of cognitive behaviour therapy and graded exercise for “CFS”, peer review at The Lancet failed to identify the same faults.Psychiatry has won the day” again - but only because once again the same people have not been subjected to sufficiently rigorous scientific scrutiny."

The full text of the document:

The full text of the document in Word:

Also, still regarding the PACE Trials publication in the Lancet, a letter entitled “Ignorance is not an option” has been sent by Invest in ME to the Editor of the Lancet, Dr Richard Horton -

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